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Squamous Cell Carcinoma Treatment London

At a glance:

Squamous Cell Carcinoma Treatment

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Symptoms:

  • Rough, scaly patches
  • Open sores
  • Wart-like growths
  • Firm bumps on the skin
  • Large, growing masses
  • Sores that don’t heal and ooze or bleed persistently
  • Painful lesions

Diagnosis:

Your dermatologist can suspect the diagnosis clinically and with the help of a dermatoscope (magnified light).

Treatment:

The appropriate squamous cell carcinoma treatment will depend on the severity of your condition.

Our clinic operates as a private surgery and is not affiliated with the NHS (National Health Service)

Squamous cell carcinoma (SCC) is the second most common type of skin cancer in the U.K. It accounts for as many as 20% of all skin cancers. Luckily, it also has a high survival rate, provided it’s detected and treated early. Still, if you or your loved one suspect SCC cancer, it’s natural to feel overwhelmed. Staying informed will help you with these feelings. Our expert consultants at Clinica London can examine and treat any skin lesion that is of concern to you.

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WHAT IS SQUAMOUS CELL CARCINOMA?


Squamous cell carcinoma is a non-melanoma skin cancer that originates in the squamous cells of the epidermis, which is the outermost layer of skin. The squamous cells are flat cells which constantly shed as new ones form. In squamous cancer, these cells start growing out of control. This can occur for several reasons, the chief being long-term sun exposure. Therefore it is most commonly seen on the eyelids, face, ears, scalp and other sun-exposed areas of skin.

How Does Squamous Cell Carcinoma Look?

Squamous cell skin cancer can look different depending on where it appears and how advanced it is. Typically, it appears as rough, scaly patches or red or wart-like growths. It can also take the form of open sores that don’t seem to heal.

Another form is a raised bump or ulcerated area on sun-exposed parts of the skin. These parts typically include the face, ears, neck, and hands. In individuals with darker skin, squamous cell carcinoma is more likely to develop in areas that are less exposed to the sun, such as the genitals.

To better understand what this cancer type looks like – and differentiate it from other skin conditions – please refer to squamous cell carcinoma pictures in different stages.

Symptoms of Squamous Cell Carcinoma


The trouble with squamous cell carcinoma symptoms lies in the fact that they can sometimes resemble other common skin conditions, such as eczema or psoriasis. As a result, you can mistake them for less serious issues.

But remember – timely detection is critical for treating SCC cancer. So, if you notice any unusual skin changes – and they don’t go away quickly – you should immediately consult a healthcare professional.

Early signs of squamous cancer can include:

  • Rough, scaly patches
  • Open sores
  • Wart-like growths
  • Firm bumps on the skin

A more advanced squamous cell carcinoma will appear with more pronounced symptoms that may include:

  • Large, growing masses
  • Sores that don’t heal and ooze or bleed persistently
  • Painful lesions

Causes and Risk Factors for Squamous Cell Carcinoma


It’s important to understand that anyone can get squamous cell carcinoma. However, there are specific causes and risk factors that can increase your likelihood of developing this type of cancer.

Key causes include:

  • UV radiation: Too much (unprotected) exposure to ultraviolet light is the leading cause of SCC. The radiation can be from the sun or other sources, such as tanning beds or lamps.
  • Exposure to harmful chemicals: Having contact with harmful chemicals like arsenic can cause squamous cell carcinoma to develop. Most commonly, these chemicals are found in industrial processes. However, you can also be exposed to arsenic naturally, such as through well water.
  • A weakened immune system: People with compromised immune systems are more likely to develop SCC. This cancer type will also grow more quickly and act more aggressively in these individuals. The weakened immune system is usually a result of having a medical condition that reduces the immune function (e.g., leukaemia), receiving chemotherapy, or using immunosuppressive medications. If the medications in question are used to prevent the rejection of a transplanted organ, the risk of SCC increases dramatically.
Photo focused on a woman's neck while a doctor check two moles on her skin

As far as risk factors go, these elements can increase your chances of developing squamous cell carcinoma:

  • Age: SCC cancer can appear in people of any age. However, the risk increases as you age (and accumulate more sun damage). That’s why most cases of squamous cell carcinoma are recorded in people over 50.
  • Skin type: While people of all skin types can develop SCC, this cancer type disproportionally affects people with lighter skin. This especially applies to individuals with blond or red hair and blue or green eyes, as well as those whose skin freckles or easily burns.
  • History of sunburns: People who have experienced severe sunburns in the past have a higher risk of developing SCC later in life. The same goes for repeated sunburns, as they can permanently damage your skin.
  • Genetic predisposition: If you have a family history of skin cancer, you’re at a higher risk of developing SCC. The same applies to specific genetic conditions, such as basal cell nevus syndrome, Muir-Torre syndrome, and epidermolysis bullosa.

Immunosuppression: After organ transplant the drugs used to prevent rejection of the transplant can reduce immunity and SCC is more commonly seen in those individuals.

Squamous Cell Carcinoma vs. Basal Cell Carcinoma


Basal cell carcinoma is the most common type of skin cancer, accounting for 80% of non-melanoma skin cancer. Like squamous cell carcinoma, it is primarily caused by over-exposure to UV rays. However, this is pretty much where the similarities between these two cancer types end.

Basal cell carcinoma

Squamous cell carcinoma

Origin

The basal cells of the epidermis

The squamous cells of the epidermis

Typical appearance

A pink or lavender bump surrounded by blood vessels

Dry, itchy, or scaly patches of skin

Aggressiveness

Slower growth, doesn’t spread to other areas of the body

Grows and spreads quickly (if invasive), particularly in immunocompromised individuals

Main risk factors

Over-exposure to ultraviolet rays, a genetic predisposition

Over-exposure to ultraviolet rays, a suppressed immune system

Treatment approaches

Topical treatment, curettage and electrodesiccation, cryotherapy, radiation therapy, surgical excision, Mohs surgery

Topical treatment, curettage and electrodesiccation,  cryotherapy, surgical excision, Mohs surgery, radiation therapy, chemotherapy and immunotherapy

How is Squamous Cell Carcinoma diagnosed?

Your dermatologist can suspect the diagnosis clinically and with the help of a dermatoscope (magnified light). To confirm the diagnosis, a small piece of the skin lesion (a biopsy) or the whole lesion (an excision biopsy) will be removed under local anaesthetic and sent to a pathologist to be examined under the microscope.

Treatment Options for Squamous Cell Carcinoma


The appropriate squamous cell carcinoma treatment will depend on the severity of your condition. At Clinica London, you can get a variety of treatment options for both early-stage cases and more invasive squamous cell carcinoma.

Topical Treatments

Topical creams or solutions can be effective in early-stage squamous cell carcinoma when the tumour is still superficial. If that’s the case, the prescribed cream or gel is applied directly to the affected area of the skin, activating the immune system to attack the cancerous cells.

Surgical Excision

If the SCC hasn’t spread, the entire tumour can be removed surgically. A part of the surrounding tissue will also be removed in the process to make sure that all the cancerous cells are removed. The ultimate goal is to ensure there are no more cancerous cells in the skin. The remaining defect in the skin can be skillfully reconstructed by our surgeons. If occurring on the face or around the eyelids, the expert oculofacial plastic surgeons at Clinica will be your first port of call. They are highly trained oculoplastic surgeons who can both remove the SCC and carry out the delicate oculoplastic reconstruction.

The oculofacial plastic surgeons (also known as oculoplastic surgeons) work closely with dermatologists.

Mohs Micrographic Surgery

Mohs surgery is the best option for removing SCCs in functionally or cosmetically important areas. These areas include the face, ears, or genital region. With Mohs surgery, your tumour gets removed in stages. This approach allows the surgeon to only remove what must be removed and to confirm that all of the cancer cells are gone before proceeding to reconstruction of the defect. For cosmetically important areas, particularly around the eyes and face, it is important to choose a surgeon with special expertise in reconstructing these delicate areas.

Oculofacial reconstruction

At Clinica London, we have expert oculofacial plastic surgeons who are highly experienced in the reconstruction of facial defects following both simple excision and after Mohs surgery SCC tumour removal. Choosing the right surgeon will allow you to have the best functional and cosmetic results.

Dermatological Surgeons

The Dermatologists carry out the Mohs surgery, usually in a central hospital with the appropriate laboratory, and then the dermatologists carry out the Mohs reconstruction, together with the oculofacial surgeons (according to which part of the body is involved), at Clinica London.

Radiation Therapy

Sometimes, surgery isn’t an option. The patient might be in poor health or the tumour might be hard to remove surgically. Whatever the case, radiation therapy can help. This therapy uses high-energy beams that target and destroy cancer cells. The good news is that it doesn’t require you to go under anaesthesia or be cut in any way. However, you might have to come in for several sessions spread over weeks.

Chemotherapy and Immunotherapy

Advanced squamous cell carcinoma is quite dangerous and challenging to treat. That’s why these cases call for more systematic treatment approaches – chemotherapy and immunotherapy. Both options involve administering drugs to the patient. In chemotherapy, these drugs aim to slow the growth of cancer cells or outright kill them. As for immunotherapy, they encourage the body’s own immune system to fight the cancer.

These treatment options also have the longest recovery times and the highest number of potential side effects.

But regardless of the treatment option(s) used, you mustn’t neglect regular follow-up care. If you’ve developed SCC once, you can easily do it again. That’s why it’s important to stay vigilant about your skin health.

Squamous Cell Carcinoma Prognosis and Stages


When it comes to squamous cell carcinoma survival rate, it’s exceptionally high. Between 95% and 98% of all SCC cases will be cured if they’re treated early. This cancer becomes more high-risk when it spreads to other parts of the body. That’s why it’s important for it to be detected in its earlier stages.

  1. Stage 0 (carcinoma in situ): The cancer cells are confined to the outer layer of the epidermis, i.e., the place where they started to develop. Treatment is typically highly successful and the prognosis is excellent.
  2. Stage 1: The cancer is 2 centimetres across or smaller and localised to the skin. Surgical treatment options are usually quite effective in this stage.
  3. Stage 2: The cancer is larger than 2 centimetres but not larger than 4 centimetres across. It also might have grown deeper into the skin. At this point, treatment is still highly effective but might involve more extensive surgery.
  4. Stage 3: The tumour is typically larger than 4 centimetres across or has spread to nearby lymph nodes. In this stage, the squamous cell carcinoma prognosis can still be good, but the treatment will be more complex and likely involve a combination of methods.
  5. Stage 4: Stage 4 is when the SCC has spread to other organs or other areas of the body. This is the most advanced stage of the tumour, and the prognosis reflects this. However, you can still attempt to control the tumour with treatments like chemotherapy or immunotherapy.

Self-Care and Prevention Tips


The good news about the squamous cell carcinoma is that it’s highly preventable. With proper sun protection and regular skin check-ups, you can reduce your risk of developing this cancer or at least detect it early.

Proper sun protection refers to:

  • Using broad-spectrum sunscreen daily
  • Limiting your exposure to UV rays
  • Wearing protective clothing and accessories
  • Avoiding peak sun hours
  • Avoiding tanning beds and sun lamps

As for regular skin check-ups, you should first do them yourself. This means thoroughly examining yourself from head to toe at least once a month. If you find suspicious spots or sores, seek immediate medical advice. However, even if you don’t, seeing a dermatologist for a professional skin exam annually is a good idea. Of course, this exam becomes a must for those who’ve already had either SCC or other forms of skin cancer.

When to See the Oculofacial Surgeon or the Dermatologist


Slight changes on your skin can be a normal occurrence. However, if your skin persistently changes texture or colour or can’t seem to heal after a few weeks, it’s time to see the oculofacial surgeon if the area affected is around the eyelids, on the face, in the scalp or on the neck. Usually, if the area affected is on the trunk, limbs or hands, one of our dermatologists is preferred. As mentioned, early detection will make all the difference in your squamous cell carcinoma prognosis.

Before and After Treatment Advice


Before Treatment

Reducing the risk of SCC is all about taking care of your skin health. The same goes for your behaviour before a squamous cell carcinoma treatment. This includes avoiding direct sun exposure and maintaining a healthy skincare routine. Most importantly, you should refrain from attempting any self-treatment, such as using unprescribed creams.

Aftercare Tips

After your squamous cell carcinoma treatment, you need to heal properly. To do so, you’ll again have to avoid sun exposure. You’ll also need to follow your healthcare provider’s instructions for wound care and follow-up appointments. Besides healing relatively quickly, this approach will help you prevent complications and reduce the risk of recurrence.

OUR CONSULTANTS


At Clinica London, our dedicated team of dermatology consultants bring a wealth of knowledge and expertise to provide you with the highest standard of care.

Our Dermatology Consultants are here to support you or your child with a variety of skin-related conditions, combining their medical expertise together with a commitment to personalised care. Contact us to make an appointment and thus take the first step towards healthier more comfortable skin.

Dr Jennifer Crawley

Consultant Dermatologist
Children & Adults

Dr Rebeca Calado

Consultant Dermatologist
Children & Adults
Specialist in Dermatovenereology

Our clinic operates as a private surgery and is not affiliated with the NHS (National Health Service)

FAQs about Squamous Cell Carcinoma

Early symptoms of squamous cell carcinoma are red patches, scaly areas, and sores that don’t heal.

Several methods can be used to treat squamous cell carcinoma. They range from topical treatments, cryotherapy, chemotherapy and surgical excision, depending on the tumour’s severity.

Yes, untreated squamous cell carcinoma can spread to deeper tissues, lymph nodes, and distant organs. If this happens, the tumour becomes more high-risk and requires more intensive treatment.

Early-stage squamous cell carcinoma has a survival rate of up to 98%.

 

SCC is typically more aggressive than basal cell carcinoma. The latter grows slower and doesn’t tend to spread.

 

Award Winning Clinic in London

Clinica London is a leading ophthalmology and dermatology medical clinic. It has a sense of passion for helping patients. The clinic’s consultants are highly skilled professionals who have received British, European, and international awards in their respective fields. Clinica is honest and offers transparent treatment advice in a relaxed and comfortable environment.

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